Flavonoid polyphenols are bioactive phytochemicals found in fruits and teas among other sources. Gao Z, Yin X and Cao Q (2026) The role and application prospects of plant-derived bioactive peptides in exercise fatigue recovery. The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Profound investigation and analysis on the SAR of the bioactive peptides from plants are necessary for translational conversion and application based on biological http://www.tothe92.co.uk/links/cannabis-legalization.html activity. Plant-derived peptides, with a PPARα stimulation effect, promote fatty acid oxidation instead of storage , 53, 62,, helping athletes to sustain a proper body composition, but also optimizing their metabolic flexibility between carbohydrate and fat use for different levels of exercise intensity and time duration. One of the favorable consequences from using plant bioactive peptides in animal and human diets is to activate peroxisome proliferator activated receptor alpha (PPARα) by up-regulating transcription factors of PPARα, which can help regulate the conversion of fatty acid during treatment (28).
The literature that was included was evaluated by two authors , S.Z. & Y.X., utilizing the Cochrane risk of bias (ROB) assessment tool. Quantitative assessments of athletic performance or physiological metrics (including heart rate), blood glucose levels, aerobic and anaerobic performance, and others must be provided by the studies. Both a control group and a protein group must be present in the included studies, with a notable difference in protein intake evident in the control group when compared to the protein group. During the selection process, studies that did not provide extractable data or were non-original, such as letters, reviews, or editorials, were excluded. Non-human studies (such as those focused on plants and animals), were eliminated from consideration. The keywords and subject headings were established through discussions between two reviewers, drawing from the Pubmed Mesh database.
It is hypothesized that an intake of protein may enhance athletic performance by improving muscle strength and endurance among athletes. This study aims to clarify the effectiveness of protein on athletic performance by integrating available evidence. A significant factor in sustaining athletic performance following high-intensity exercise has been identified as muscle glycogen storage.
Key takeaways

Schematic of plant extracts and their effects on exercise, including reducing muscle damage, improving recovery, and increasing energy availability, with examples and specific benefits. This underscores the importance of balancing ROS scavenging with preservation of adaptive signaling—a key consideration for plant-based antioxidant supplementation in sports nutrition. For practical application, this means the blend is effective even if consumed 30–60 min after training (e.g., by athletes who experience gastrointestinal discomfort with immediate post-exercise whey intake). These additives can be classified into various categories, including herbal extracts, essential oils, and whole-plant powders, each offering unique properties and potential health benefits (7–9). However, many individuals face challenges in achieving optimal exercise performance due to factors such as oxidative stress, inflammation, and metabolic disturbances (3, 4). Vegetable oils such as olive oil and palm oil provide lipids, while fruit and vegetables contribute vitamins and minerals to the diet.
There are an estimated 400,000 different species of plants known to science, and new species are continually being described, particularly from tropical areas of the world. Our editors will review what you’ve submitted and determine whether to revise the article. Feedback Type Select a type (Required) Factual Correction Spelling/Grammar Correction Link Correction Additional Information Other Let us know if you have suggestions to improve this article (requires login). Some plants that produce windblown pollen, including grasses, invoke allergic reactions in people who suffer from hay fever.
These findings suggest that high-fat diets quickly disrupt cellular metabolism (reducing energy expenditure), while a low-fat, plant-based diet has the opposite effect, increasing postprandial energy expenditure. In a 5-day experiment in human volunteers, a 55%-fat diet led to a marked increase in circulating endotoxins and, in turn, to a significant impairment of postprandial cellular glucose oxidation . This is important for reducing the risk of type 2 diabetes and improving glycemic control in individuals with diabetes — which is a major contributor to atherosclerosis.
Authors of the studies were contacted for raw data; if this data was not provided — it was obtained from reported figures through WebPlotDigitizer. The GSSI provided an honorarium for involvement in both the meeting and the article’s preparation. All authors are accountable for the integrity of every aspect of the article. Moreover, certain selected medicinal plants may have the potential to enhance performance and boost recovery. Given that training and competition can create structural and functional imbalances due to intense exertion, CBD consumption might facilitate the restoration of physical performance.
AI tools may have been used in the translation or editing of this article. Sycheva—editing, approval of the final version of the article. S.N. Shlykov—concept and design of the study — interpretation of results, writing of the article. To date, there is little research on cannabis for sports-related injuries or sports specific applications, just a lot of early work on other conditions.
The tart cherry powder exhibited the highest total phenolic content at 25, 26, 27, yet none of these studies indicated effectiveness in enhancing recovery post-exercise. No improvements in recovery were observed in the days following exercise for two studies using tart cherry concentrate gel or in four studies examining tart cherry powder , refer to Tables 1 and 2,. Studies employing juice from concentrate or fresh-frozen cherries have consistently demonstrated improvements in recovery, with at least one positive outcome noted in 9 out of 11 investigations.
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Top Natural Supplements for Recovering Muscles.
Subgroup analyses were conducted to provide solid evidence to explain the results of the meta-analysis. The meta-analysis employed both the fixed-effects model and the random-effects model to investigate the impact of protein intake on sports performance. A systematic database search was conducted to identify randomized controlled trials (RCTs) examining the effects of protein intake on athletes’ performance. This study aimed to explore the relationship between protein intake and athletic performance.
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